ganR [2017-06-16 18:36:21]

transcriptional repressor of the galactan utilization operon

locus: BSU34170

pI: 5.40

mw: 37.31 kDa

protein length: 330 aa

gene length: 990 bp

function: regulation of galactan utilization

product: transcriptional repressor ([SW|LacI family])

essential: no

synonyms: yvfJ,ganR

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.24|Utilization of galactan]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

Gene

Coordinates: 3,508,659 → 3,509,651

The protein

Protein family

• [SW|LacI family]

Effectors of protein activity

• released from DNA upon binding of galactobiose [pubmed|22383849,27501980]

Expression and Regulation

Operons

• genes: [gene|1F787F70C87DEB221709579122D63C2322A84E56|ganR]
  description: [Pubmed|22383849]

  regulatory mechanism

  • [protein|1F787F70C87DEB221709579122D63C2322A84E56|GanR]: repression, [pubmed|22383849], in [regulon|1F787F70C87DEB221709579122D63C2322A84E56|GanR regulon]

  regulation

  • induced by galactan (binding of galactobiose to [protein|1F787F70C87DEB221709579122D63C2322A84E56|GanR]) [Pubmed|28617843]

Biological materials

Mutant

• GP815 (spc) available in the [SW|Stülke] lab

References

• 2104611,9287030,27501980,22383849